Hydrogen generators are transforming chromatography labs, offering significant advantages over traditional gas cylinders. In this Ask the Expert blog post, we delve into the world of hydrogen generators with Laura Trio from Claind SRL, exploring their benefits, safety features, and applications in chromatography.
Advantages of Hydrogen Generators
The shift from gas cylinders to hydrogen generators brings substantial benefits to chromatography labs:
- Cost-Effective: Hydrogen generators eliminate the need for expensive plant certifications required for cylinder storage, particularly in the EU. Learn more: Cost Benefit Analysis: Hydrogen Generators vs Gas Cylinders
- Enhanced Safety: By producing hydrogen on-demand, generators remove the risks associated with cylinder transportation and storage.
- Improved Efficiency: Generators ensure a consistent gas supply, eliminating concerns about running out of stock or managing cylinder replacements.
- Space-Saving: With no need for cylinder storage areas, labs can optimize their space utilization.
Built-In Safety Features
Claind's hydrogen generators incorporate multiple safety mechanisms:
- Pressure Switch: Halts production if pressure exceeds set levels.
- Thermostat: Stops operation if cell temperature reaches critical levels.
- Vent System: Capable of clearing out all produced hydrogen in case of internal leakage.
These features work in tandem to create a virtually risk-free environment for hydrogen production and use in the lab.
Maintenance and Lifespan
Hydrogen generators require minimal maintenance, with replacement needs varying based on usage:
| Component | Replacement Interval |
| Resin bed | Every 6 months |
| Water circulation pump | Every 9,000 working hours |
| Desiccant | Every 20,000 liters of produced H2 |
Chromatography Applications
Hydrogen generators are particularly beneficial in carrier gas applications. The trend of switching from helium to hydrogen as a carrier gas is gaining momentum due to:
- Faster Analysis: Hydrogen provides shorter analysis times within a linear speed range.
- Higher Efficiency: Hydrogen is more efficient than helium in chromatography applications.
- Supply Stability: Hydrogen generators help avoid the looming shortage problems associated with helium.
Lab Environment Considerations
While hydrogen generators are robust, extreme environmental conditions can affect their performance:
- High temperatures (>25°C) and humidity (>70%) may impact desiccant lifespan.
- Under standard lab conditions, the desiccant typically lasts until the expected 20,000 liters of hydrogen are produced.
- In more challenging environments, earlier desiccant maintenance may be necessary.
By addressing safety concerns, offering cost savings, and providing a reliable gas supply, hydrogen generators are proving to be invaluable tools in modern chromatography labs. As the field continues to evolve, these generators are poised to play an increasingly crucial role in advancing chromatographic techniques and research.
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