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Why Nitrogen Generators are Gaining Popularity

Written by Organomation | June 18, 2024

 

In the ever-evolving landscape of laboratory technologies, the future of laboratory gases is taking a notable turn towards innovation and efficiency. Among the array of gases used in laboratories, nitrogen has emerged as a critical component due to its inert properties and wide range of applications. As the demand for high-purity nitrogen continues to grow, nitrogen generators are gaining popularity, offering an array of benefits that are revolutionizing how commercial and academic laboratories operate, particularly in fields such as environmental testing.

→ Discover: Nitrogen Generators: Everything you need to know
Product featured in photo above: NITRO-GEN Benchtop Nitrogen Generator

 

The Growing Demand for Nitrogen

Nitrogen is indispensable in numerous laboratory processes. It is used in gas chromatography, liquid chromatography-mass spectrometry (LC-MS), and as a carrier gas in many other analytical techniques. Its inert nature makes it ideal for creating controlled environments, preserving samples, and ensuring the accuracy and reliability of experimental results.

As laboratories strive for greater efficiency and precision, the demand for high-purity nitrogen has increased. Traditionally, nitrogen has been supplied in gas cylinders or bulk liquid form, but these methods have significant drawbacks, including supply chain logistics, storage challenges, and safety concerns. This is where nitrogen generators come into play.

 

Nitrogen Generators and Their Advantages

Nitrogen generators are devices that produce nitrogen gas from compressed air on-site, providing a continuous supply of nitrogen at the required purity levels. These systems use technologies such as pressure swing adsorption (PSA) or membrane separation to filter out oxygen and other gases, delivering nitrogen that meets the stringent requirements of modern laboratory applications.

→ Discover: Is generating nitrogen in my lab worthwhile? 

We discuss the benefit provided by nitrogen generators across several pages on Organomation.com but below is a quick summary:

Cost Efficiency of Generators Over Cylinders

One of the most compelling reasons for the shift towards nitrogen generators is cost efficiency. Traditional nitrogen supply methods involve recurring costs for purchasing, delivering, and storing gas cylinders or liquid nitrogen. In contrast, nitrogen generators represent a one-time capital investment with minimal ongoing operational costs. Laboratories can produce nitrogen on-demand, eliminating the need for expensive and time-consuming gas deliveries.

Continuous Supply of Nitrogen Gas

Nitrogen generators provide a continuous and reliable supply of nitrogen, ensuring that laboratory operations are never disrupted due to gas shortages. This reliability is crucial for laboratories with high nitrogen consumption or those conducting long-term experiments. The ability to produce nitrogen on-site also reduces the dependency on external suppliers and mitigates risks associated with supply chain disruptions.

Enhanced Laboratory Safety

Handling and storing high-pressure gas cylinders or liquid nitrogen pose significant safety risks. Accidents related to gas leaks or improper handling can lead to serious injuries and even fatalities. Nitrogen generators enhance safety by reducing the need for high-pressure storage and minimizing the risk of leaks. Additionally, on-site nitrogen generation means that laboratories no longer need to manage the logistics of transporting hazardous materials.

Reduced Environmental Impact

Environmental sustainability is a growing concern across all industries, and laboratories are no exception. Nitrogen generators contribute to environmental conservation by reducing the carbon footprint associated with the production, transportation, and disposal of gas cylinders. By generating nitrogen on-site, laboratories can significantly cut down on emissions and contribute to greener operations.

→ Discover: Do nitrogen generators actually reduce your carbon footprint?

Customizable Purity Levels

Different laboratory applications require different purity levels of nitrogen. Nitrogen generators offer the flexibility to adjust the purity of the nitrogen produced to meet specific needs, ranging from 95% to 99.999% purity. This customization ensures that laboratories can maintain the highest standards of accuracy and reliability in their work.

 

Nitrogen Generators in Various Laboratory Settings

→ Discover: Why nitrogen is ideal for drying test samples

Environmental Testing Supported by Nitrogen Generators

In environmental testing laboratories, where the analysis of air, water, and soil samples demands precise and reliable results, nitrogen generators have become invaluable. The ability to produce high-purity nitrogen on-site ensures consistent analytical performance, which is crucial for detecting pollutants, contaminants, and other environmental hazards. Moreover, the cost savings and safety benefits enable environmental testing facilities to allocate more resources towards expanding their testing capabilities and enhancing overall quality.

Nitrogen Generators in Academic Research

For academic laboratories, generators provide a cost-effective and reliable N2 generation solution that supports a wide range of research activities. From supporting advanced analytical techniques to ensuring the safe preservation of samples, nitrogen generators enhance the operational efficiency of academic institutions. The reduced environmental impact aligns with the sustainability goals of many universities, making nitrogen generators an attractive option for research facilities looking to modernize their operations.

Pharmaceutical Labs Supported by Nitrogen Generators

In pharmaceutical research and development, nitrogen generators play a critical role. They provide high-purity nitrogen necessary for synthesizing and analyzing new drug compounds, ensuring the accuracy and safety of the development process. Nitrogen generators support a range of applications, including formulation development, stability testing, and packaging. The ability to produce nitrogen on-site helps pharmaceutical laboratories maintain stringent quality control standards while reducing operational costs and enhancing safety.

Nitrogen Generators Aiding Food and Beverage Testing

Food and beverage laboratories use nitrogen for various applications, including packaging, preservation, and analytical testing. Nitrogen generators ensure a consistent supply of high-purity nitrogen for modified atmosphere packaging (MAP), which extends the shelf life of products by inhibiting oxidation and microbial growth. Additionally, nitrogen is used in mass spectrometry and other analytical techniques to ensure the safety and quality of food products. On-site nitrogen generation helps these laboratories meet industry standards while optimizing operational efficiency.

Biotechnology and Life Sciences Enabled by Nitrogen Gas

Biotechnology and life sciences laboratories rely on nitrogen for processes such as cell culture, cryopreservation, and lyophilization. Nitrogen generators provide a reliable source of nitrogen that is essential for maintaining the integrity and viability of biological samples. For instance, in cryopreservation, high-purity nitrogen is used to preserve cells, tissues, and other biological materials at ultra-low temperatures. The ability to produce nitrogen on-site enhances the reliability and efficiency of these critical processes.

Nitrogen Generators in Chemical Analysis

Chemical laboratories utilize nitrogen in various analytical techniques, including gas chromatography (GC) and liquid chromatography-mass spectrometry (LC-MS). High-purity nitrogen is crucial for carrier and makeup gases in GC, ensuring accurate and reliable separation of chemical compounds. In LC-MS, nitrogen is used as a drying and nebulizing gas to improve ionization efficiency and sensitivity. Nitrogen generators provide a continuous supply of high-purity nitrogen, enabling chemical laboratories to achieve precise and reproducible results.

 

Cutting-Edge Research Enabled by Nitrogen Generators

1. Genomics and Proteomics:

In the field of genomics and proteomics, the precision and reliability of nitrogen generators are enabling researchers to conduct advanced studies on genetic material and proteins. High-purity nitrogen is essential for maintaining the stability of samples during mass spectrometry analysis. For example, nitrogen generators are supporting groundbreaking research in cancer genomics, where the identification of genetic mutations and protein biomarkers is crucial for developing targeted therapies.

2. Environmental Science:

Nitrogen generators are revolutionizing environmental science research. Laboratories analyzing air quality and environmental pollutants rely on high-purity nitrogen to calibrate instruments and ensure accurate measurements. Recent studies on the impact of microplastics in marine environments and the effects of air pollution on human health have greatly benefited from the continuous and reliable supply of nitrogen provided by on-site generators.

3. Drug Discovery and Development:

In pharmaceutical research, nitrogen generators are instrumental in drug discovery and development. The production of high-purity nitrogen is critical for synthesizing and analyzing new drug compounds. Researchers are utilizing nitrogen generators to enhance the efficiency of high-throughput screening processes, leading to the rapid identification of potential drug candidates. This technology is accelerating the development of treatments for diseases such as Alzheimer's, diabetes, and infectious diseases.

4. Advanced Material Science:

The field of material science is experiencing significant advancements due to the availability of high-purity nitrogen. Researchers are exploring the properties of nanomaterials, graphene, and other advanced materials with applications ranging from electronics to renewable energy. Nitrogen generators ensure a controlled and inert atmosphere, which is essential for experiments that require precise environmental conditions.

 

The Future Outlook of Nitrogen Generators

As technology continues to advance, the integration of nitrogen generators into laboratory infrastructure is expected to become even more seamless and sophisticated. Innovations in generator design, energy efficiency, and automation will further enhance their appeal. For example, future nitrogen generators may incorporate artificial intelligence to optimize nitrogen production based on real-time demand and usage patterns, improving efficiency and reducing energy consumption.

Additionally, as awareness grows about the benefits of on-site nitrogen generation, it is likely that more laboratories will transition away from traditional gas supply methods. The trend towards sustainable and self-sufficient laboratory operations will drive the adoption of nitrogen generators, contributing to the overall advancement of scientific research.

In conclusion, the future of laboratory gases is undoubtedly moving towards on-site generation, with nitrogen generators leading the charge. The cost efficiency, continuous supply, enhanced safety, environmental benefits, and customizable purity levels make nitrogen generators a superior choice for a wide range of laboratory settings. As the demand for high-purity nitrogen continues to rise, adopting nitrogen generators will be a crucial step in advancing laboratory technologies and achieving operational excellence. The innovative research enabled by these generators today is just the beginning, with the next decade promising even more remarkable breakthroughs and applications.